Articles

Developing a clinical decision support for opioid use disorders: a NIDA center for the clinical trials network working group report

There is an urgent need for strategies to address the US epidemic of prescription opioid, heroin and fentanyl-related overdoses, misuse, addiction, and diversion. Evidence-based treatment such as medications f...

Authors: Gavin B. Bart, Andrew Saxon, David A. Fiellin, Jennifer McNeely, John P. Muench, Christopher W. Shanahan, Kristen Huntley and Robert E. Gore-Langton

Use of urinary naloxone levels in a single provider practice: a case study

Urine drug monitoring for medications for opioid use disorder (MOUD) such as buprenorphine can help to support treatment adherence. The practice of introducing unconsumed medication directly into urine (known ...

Authors: Jill S. Warrington, Kaitlyn Booth, Gregory S. Warrington and Samuel Francis-Fath

Case report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach

The requirement for moderate withdrawal prior to initiation can be a barrier to buprenorphine/naloxone induction.

Authors: Jennifer Rozylo, Keren Mitchell, Mohammadali Nikoo, S. Elise Durante, Skye P. Barbic, Daniel Lin, Steve Mathias and Pouya Azar

Design of a randomized controlled trial to Link Infectious and Narcology Care (LINC-II) in St. Petersburg, Russia

If Russia is to achieve the UNAIDS 90-90-90 HIV targets, better approaches to engage, effectively treat, and retain patients in care are needed. This paper describes the protocol of a randomized controlled tri...

Authors: Natalia Gnatienko, Dmitry Lioznov, Anita Raj, Elena Blokhina, Sydney Rosen, Debbie M. Cheng, Karsten Lunze, Sally Bendiks, Ve Truong, Natalia Bushara, Olga Toussova, Emily Quinn, Evgeny Krupitsky and Jeffrey H. Samet

Building a Group-Based Opioid Treatment (GBOT) blueprint: a qualitative study delineating GBOT implementation

Group-Based Opioid Treatment (GBOT) has recently emerged as a mechanism for treating patients with opioid use disorder (OUD) in the outpatient setting. However, the more practical “how to” components of succes...

Authors: Randi Sokol, Mark Albanese, Aaronson Chew, Jessica Early, Ellie Grossman, David Roll, Greg Sawin, Dominic J. Wu and Zev Schuman-Olivier

Outcomes of a novel office-based opioid treatment program in an internal medicine resident continuity practice

The integration of opioid use disorder (OUD) care and competencies in graduate medical education training is needed. Previous research shows improvements in knowledge, attitudes, and practices after exposure t...

Authors: Jarratt D. Pytell, Megan E. Buresh and Ryan Graddy

Longitudinal analysis of HIV-risk behaviors of participants in a randomized trial of prison-initiated buprenorphine

It has been estimated that approximately 15% of people who are incarcerated in the US have histories of opioid use disorder. Relapse to opioid use after release from prison poses a serious risk of HIV infectio...

Authors: Thomas R. Blue, Michael S. Gordon, Robert P. Schwartz, Kathryn Couvillion, Frank J. Vocci, Terrence T. Fitzgerald and Kevin E. O’Grady

Priming primary care providers to engage in evidence-based discussions about cannabis with patients

Cannabis use has become increasingly common in the U.S. in recent years, with legalization for medical and recreational purposes expanding to more states. With this increase in use and access, providers should...

Authors: Devan Kansagara, William C. Becker, Chelsea Ayers and Jeanette M. Tetrault

Sort of a nice distance: a qualitative study of the experiences of therapists working with internet-based treatment of problematic substance use

Internet interventions have been developed and tested for several psychiatric and somatic conditions. Few people with substance use disorders receive treatment and many drug users say that they would prefer ge...

Authors: Veronica Ekström and Magnus Johansson

The feasibility of using smartphones and mobile breathalyzers to monitor alcohol consumption among people living with HIV/AIDS

For people living with HIV/AIDS (PLWHA), alcohol consumption is associated with poor treatment outcomes and medication adherence. This pilot study examined the feasibility of using smartphones and mobile Bluet...

Authors: Carolyn Lauckner, Erica Taylor, Darshti Patel and Alexis Whitmire

Staff perceptions of prescription and over-the-counter drug dependence services in England: a qualitative study

Dependence to prescription and over-the-counter (OTC) drugs represents an increasing public health and clinical problem both in England and internationally. However, relatively little is known about those affe...

Authors: Heidi Coombes and Richard J. Cooper

How to overcome political and legal barriers to the implementation of a drug consumption room: an application of the policy agenda framework to the Belgian situation

For more than 30 years, drug consumption rooms (DCRs) have been implemented in Western countries. DCRs are supported by a large body of evidence about public safety and public health effectiveness. However, a ...

Authors: Pierre Smith, Louis Favril, Dominique Delhauteur, Freya Vander Laenen and Pablo Nicaise

Electronic self-administered screening for substance use in adult primary care patients: feasibility and acceptability of the tobacco, alcohol, prescription medication, and other substance use (myTAPS) screening tool

The TAPS Tool is a substance use screening and brief assessment instrument that was developed for use in primary care medical settings. It is one of the first screening instruments to provide rapid assessment ...

Authors: Angéline Adam, Robert P. Schwartz, Li-Tzy Wu, Geetha Subramaniam, Eugene Laska, Gaurav Sharma, Saima Mili and Jennifer McNeely

A cross sectional survey of internet use among a highly socially disadvantaged population of tobacco smokers

Tobacco smoking is highest among population groups which are the most socially disadvantaged. Internet-based smoking cessation programs have been found to be effective, though rates of internet access are not ...

Authors: Sam McCrabb, Laura Twyman, Kerrin Palazzi, Ashleigh Guillaumier, Christine Paul and Billie Bonevski

Perceptions of extended-release naltrexone, methadone, and buprenorphine treatments following release from jail

Few studies have documented patient attitudes and experiences with extended-release naltrexone (XR-NTX) opioid relapse prevention in criminal justice settings. This study assessed barriers and facilitators of ...

Authors: Melissa Velasquez, Mara Flannery, Ryan Badolato, Alexandria Vittitow, Ryan D. McDonald, Babak Tofighi, Ann R. Garment, Jonathan Giftos and Joshua D. Lee

Proceedings of the 16th annual conference of INEBRIA

Authors:

Implementing risk stratification to the treatment of adolescent substance use among youth involved in the juvenile justice system: protocol of a hybrid type I trial

Youth involved in the juvenile justice system (YIJJ) have high rates of substance use problems; however, rates of YIJJ engagement in substance use services is low. Barriers to service engagement include lack o...

Authors: Matthew C. Aalsma, Allyson L. Dir, Tamika C. B. Zapolski, Leslie A. Hulvershorn, Patrick O. Monahan, Lisa Saldana and Zachary W. Adams

Leveraging the role of community pharmacists in the prevention, surveillance, and treatment of opioid use disorders

The global rise in opioid-related harms has impacted the United States severely. Current efforts to manage the opioid crisis have prompted a re-evaluation of many of the existing roles in the healthcare system...

Authors: Paxton Bach and Daniel Hartung

Ask about smoking, not quitting: a chronic disease approach to assessing and treating tobacco use

Tobacco use is a chronic relapsing disease, and remains the leading cause of preventable death in much of the world. Increasingly, tobacco use, chiefly cigarette smoking, is being framed as a chronic disease, ...

Authors: Steven L. Bernstein and Benjamin A. Toll

Development of a tailored, telehealth intervention to address chronic pain and heavy drinking among people with HIV infection: integrating perspectives of patients in HIV care

Chronic pain and heavy drinking commonly co-occur and can influence the course of HIV. There have been no interventions designed to address both of these conditions among people living with HIV (PLWH), and non...

Authors: Tibor P. Palfai, Jessica L. Taylor, Richard Saitz, Maya P. L. Kratzer, John D. Otis and Judith A. Bernstein

Physicians’ satisfaction with providing buprenorphine treatment

Buprenorphine is a critically important treatment for addressing the opioid epidemic, but there are virtually no studies of physicians’ job satisfaction with providing buprenorphine. Physicians’ job satisfacti...

Authors: Hannah K. Knudsen, Randy Brown, Nora Jacobson, Julie Horst, Jee-Seon Kim, Elizabeth Collier, Sanford Starr, Lynn M. Madden, Eric Haram, Alexander Toy and Todd Molfenter

Commentary on physicians’ satisfaction with providing buprenorphine treatment by Knudsen et al.

Authors: Gavin Bart and Jeffrey Samet

An online alcohol and risky sex prevention program for college students studying abroad: study protocol for a randomized controlled trial

This study protocol describes a proposed randomized controlled trial that builds upon a successful pilot intervention study to address problematic and dangerous drinking among young adult college students stud...

Authors: Eric R. Pedersen, Elizabeth J. D’Amico, Joseph W. LaBrie, Coreen Farris, David J. Klein and Beth Ann Griffin

Medicaid expansion and treatment for opioid use disorders in Oregon: an interrupted time-series analysis

The study examined the association of the Affordable Care Act’s 2014 Medicaid expansion on the use of psychosocial services and pharmacotherapies for opioid use disorders among Oregon Medicaid recipients.

Authors: Dennis McCarty, Yifan Gu, John W. McIlveen and Bonnie K. Lind

Does an adapted Dialectical Behaviour Therapy skills training programme result in positive outcomes for participants with a dual diagnosis? A mixed methods study

Treating severe emotional dysregulation and co-occurring substance misuse is challenging. Dialectical behaviour therapy (DBT) is a comprehensive and evidence-based treatment for borderline personality disorder...

Authors: Daniel Flynn, Mary Joyce, Ailbhe Spillane, Conal Wrigley, Paul Corcoran, Aoife Hayes, Marian Flynn, David Wyse, Barry Corkery and Brid Mooney

Rural access to MAT in Pennsylvania (RAMP): a hybrid implementation study protocol for medication assisted treatment adoption among rural primary care providers

The continued escalation of opioid use disorder (OUD) calls for heightened vigilance to implement evidence-based care across the US. Rural care providers and patients have limited resources, and a number of ba...

Authors: Gerald Cochran, Evan S. Cole, Jack Warwick, Julie M. Donohue, Adam J. Gordon, Walid F. Gellad, Todd Bear, David Kelley, Ellen DiDomenico and Jan Pringle

Correction to: Emergency department screening and interventions for substance use disorders

In the version of this article that was originally published [1], some information in the “Background” section was erroneously omitted.

Authors: Kathryn Hawk and Gail D’Onofrio

Implementing alcohol use disorder pharmacotherapy in primary care settings: a qualitative analysis of provider-identified barriers and impact on implementation outcomes

Despite the high prevalence of alcohol use disorders (AUDs), in 2016, only 7.8% of individuals meeting diagnostic criteria received any type of AUD treatment. Developing options for treatment within primary ca...

Authors: Hildi J. Hagedorn, Jennifer P. Wisdom, Heather Gerould, Erika Pinsker, Randall Brown, Michael Dawes, Eric Dieperink, Donald Hugh Myrick, Elizabeth M. Oliva, Todd H. Wagner and Alex H. S. Harris

Factors associated with willingness to wear an electronic overdose detection device

North America is in the midst of an opioid overdose epidemic. Although take-home naloxone and other measures have been an effective strategy to reduce overdoses, many events are unwitnessed and mortality remai...

Authors: Keith Ahamad, Huiru Dong, Cheyenne Johnson, Kanna Hyashi, Kora DeBeck, M. J. Milloy and Evan Wood

Short screening tools for risky drinking in Aboriginal and Torres Strait Islander Australians: modified AUDIT-C and a new approach

Alcohol consumption among Indigenous Australians can involve a stop-start pattern of drinking, with consumption well above recommended guidelines on each occasion. Such intermittent drinking patterns can make ...

Authors: K. S. Kylie Lee, James H. Conigrave, Scott Wilson, Jimmy Perry, Sarah Callinan, Robin Room, Tanya N. Chikritzhs, Tim Slade, Noel Hayman, Geoffrey Leggat and Katherine M. Conigrave

HIV care provider perceptions and approaches to managing unhealthy alcohol use in primary HIV care settings: a qualitative study

HIV care providers often serve as the specialist and the primary care point-of-contact for persons living with HIV (PLWH) and unhealthy alcohol use. The purpose of the present qualitative study was to understa...

Authors: Natalie E. Chichetto, Zachary L. Mannes, Megan K. Allen, Robert L. Cook and Nicole Ennis

Low barrier buprenorphine treatment for persons experiencing homelessness and injecting heroin in San Francisco

Opioid overdose is a leading cause of death in persons experiencing homelessness (PEH), despite effective medications for opioid use disorder (OUD). In 2016, the San Francisco Street Medicine Team piloted a lo...

Authors: Jamie Carter, Barry Zevin and Paula J. Lum

Primary care engagement is associated with increased pharmacotherapy prescribing for alcohol use disorder (AUD)

Primary care provider skills such as screening, longitudinal monitoring, and medication management are generalizable to prescribing alcohol use disorder (AUD) pharmacotherapy. The association between primary c...

Authors: Paul J. Joudrey, Mat Kladney, Chinazo O. Cunningham and Marcus A. Bachhuber

Buprenorphine unobserved “home” induction: a survey of Ontario’s addiction physicians

Ontario patients on opioid agonist treatment (OAT) are often prescribed methadone instead of buprenorphine, despite the latter’s superior safety profile. Ontario OAT providers were surveyed to better understan...

Authors: Anita Srivastava, Meldon Kahan, Pamela Leece and Alison McAndrew

Asking about the last four drinking occasions on a tablet computer as a way to record alcohol consumption in Aboriginal and Torres Strait Islander Australians: a validation

Alcohol consumption among Indigenous Australians can be irregular, depending on social and geographic context. The Finnish method uses the last four drinking occasions to estimate drinking quantity and pattern...

Authors: K. S. Kylie Lee, James H. Conigrave, Sarah Callinan, Scott Wilson, Robin Room, Jimmy Perry, Tim Slade, Tanya N. Chikritzhs, Noel Hayman, Teagan Weatherall, Geoffrey Leggat, Dennis Gray and Katherine M. Conigrave

A conceptual model for understanding post-release opioid-related overdose risk

Post-release opioid-related overdose mortality is the leading cause of death among people released from jails or prisons (PRJP). Informed by the proximate determinants framework, this paper presents the Post-R...

Authors: Paul J. Joudrey, Maria R. Khan, Emily A. Wang, Joy D. Scheidell, E. Jennifer Edelman, D. Keith McInnes and Aaron D. Fox

Intervention for alcohol use disorders at an HIV care clinic in Harare: a pilot and feasibility study

Alcohol use in HIV infected patients is associated with risky sexual behaviour, poor adherence to Highly Active Antiretroviral Therapy, treatment failure and increased physiologic harm. The objectives of the s...

Authors: Munyaradzi Madhombiro, Bazondlile Dube, Michelle Dube, Moleen Zunza, Dixon Chibanda, Simbarashe Rusakaniko and Soraya Seedat

“They didn’t give up on me”: a women’s transitions clinic from the perspective of re-entering women

Women recently released from incarceration have increased rates of co-occurring substance use, physical health, and mental health disorders. During re-entry, they face challenges navigating needed health servi...

Authors: Katherine Thomas, John L. Wilson, Precious Bedell and Diane S. Morse

Development of a social media-based intervention targeting tobacco use and heavy episodic drinking in young adults

Tobacco use and heavy episodic drinking (HED) commonly co-occur in young adults. We developed and tested usability of the Smoking Tobacco and Drinking (STAND) intervention for young adults delivered on Facebook.

Authors: Danielle E. Ramo, Meredith C. Meacham, Manpreet Kaur, Ella S. Corpuz, Judith J. Prochaska and Derek D. Satre

Increased demand for amphetamine treatment in rural Australia

A substantial increase in substance treatment episodes for methamphetamine problems suggests characteristics of the treatment population could have changed and that targeted treatment programs are required. To...

Authors: Julaine Allan, Ryan H. L. Ip, Michael Kemp and Nicole Snowdon

Provider and patient perspectives on barriers to buprenorphine adherence and the acceptability of video directly observed therapy to enhance adherence

Buprenorphine effectively reduces opioid craving and illicit opioid use. However, some patients may not take their medication as prescribed and thus experience suboptimal outcomes. The study aim was to qualita...

Authors: Margo E. Godersky, Andrew J. Saxon, Joseph O. Merrill, Jeffrey H. Samet, Jane M. Simoni and Judith I. Tsui

Identification and management of alcohol use and illicit substance use in outpatient psychiatric clinics in Sweden: a national survey of clinic directors and staff

Swedish national guidelines recommend that all health care settings systematically screen patients for alcohol use and illicit substance use. When hazardous use is identified, it should immediately be addresse...

Authors: Christopher Sundström, Elisabeth Petersén, Kristina Sinadinovic, Peter Gustafsson and Anne H. Berman

Utilization of addiction treatment among U.S. adults with history of incarceration and substance use disorders

The high prevalence of substance use disorders (SUDs) among incarcerated adults in the U.S. is well-known, but there has been less examination of SUD treatment and rates of incarceration among the population o...

Authors: Jack Tsai and Xian Gu

Linking women experiencing incarceration to community-based HIV pre-exposure prophylaxis care: protocol of a pilot trial

Women experiencing incarceration (WEI) engage in high rates of sex- and drug-related behavior that places them at risk for HIV. Pre-exposure prophylaxis (PrEP) is an efficacious means of reducing HIV acquisiti...

Authors: Susan E. Ramsey, Evan G. Ames, Lauren Brinkley-Rubinstein, Anne M. Teitelman, Jennifer Clarke and Clair Kaplan

Illicit substance use after release from prison among formerly incarcerated primary care patients: a cross-sectional study

More than 80% of people in jail or prison report having used illicit substances in their lifetimes. After release from incarceration, resumption of substance use carries risks, including parole revocation, exa...

Authors: Adam Chamberlain, Sylviah Nyamu, Jenerius Aminawung, Emily A. Wang, Shira Shavit and Aaron D. Fox

Study protocol for a pragmatic trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) model for engaging patients in opioid use disorder treatment

Treatment for opioid use disorder (OUD) is highly effective, yet it remains dramatically underutilized. Individuals with OUD have disproportionately high rates of hospitalization and low rates of addiction tre...

Authors: Jennifer McNeely, Andrea B. Troxel, Hillary V. Kunins, Donna Shelley, Joshua D. Lee, Alexander Walley, Zoe M. Weinstein, John Billings, Nichola J. Davis, Roopa Kalyanaraman Marcello, Bruce R. Schackman, Charles Barron and Luke Bergmann

Strategies to increase implementation of pharmacotherapy for alcohol use disorders: a structured review of care delivery and implementation interventions

Effective medications for treating alcohol use disorders (AUD) are available but underutilized. Multiple barriers to their provision have been identified, and optimal strategies for addressing and overcoming b...

Authors: Emily C. Williams, Theresa E. Matson and Alex H. S. Harris

An evaluation of the maintenance to abstinence (MTA) program in achieving abstinence in opioid users and improving mental health and quality of life

Residential opioid rehabilitation aims to improve the mental health and quality of life of opioid users through abstinence and residential program participation. This study aimed to determine the depression, a...

Authors: Madeleine M. Southey, Trent Rees, Margaret Rolfe and Sabrina Pit

Patient and provider perspectives on implementation barriers and facilitators of an integrated opioid treatment and HIV care intervention

In Dar es Salaam Tanzania, the first opioid treatment program (OTP) in Sub-Saharan Africa, had very high rates of enrollment of people who use drugs (PWUD) but low rates of antiretroviral therapy (ART) initiat...

Authors: Alexis Cooke, Haneefa Saleem, Saria Hassan, Dorothy Mushi, Jessie Mbwambo and Barrot Lambdin

Tobacco use among non-elderly adults with and without criminal justice involvement in the past year: United States, 2008–2016

Tobacco use remains the leading cause of preventable disease and death in the United States and is concentrated among disadvantaged populations, including individuals with a history of criminal justice involve...

Authors: Tyler N. A. Winkelman, Katherine Diaz Vickery and Andrew M. Busch