Table 1 Sample characteristics, by trial stage
Eligible (n = 92) | Enrolled (n = 67) | Engaged | Retained (n = 43) | ||
|---|---|---|---|---|---|
All (n = 58) | Received med (n = 43) | ||||
(1) | (2) | (3a) | (3b) | (4) | |
Demographics | |||||
Age (years) | 60.0 | 59.7 | 59.2 | 58.8 | 58.9 |
Female sex (%) | 66.3 | 70.1 | 72.4 | 72.1 | 72.1 |
Black race (%) | 79.3 | 79.1 | 81.0 | 76.7 | 81.4 |
High school graduate (%) | 72.7 | 75.0 | 78.2 | 78.0 | 78.0 |
Household income < $15,000 (%) | 68.2 | 65.1 | 63.6 | 60.0 | 63.4 |
Smoking history and attitudes | |||||
Cigarettes per day | 13.4 | 13.8 | 13.5 | 14.8 | 13.7 |
Age started smoking (years) | 17.6 | 17.3 | 17.4 | 17.1 | 16.7 |
Time to first cigarette ≤ 30 min (%) | 68.5 | 68.7 | 69.0 | 74.4 | 62.8 |
Planning to quit smoking (%) | 63.5 | 63.0 | 64.1 | 64.5 | 58.6 |
Confidence in quitting (1–5) | 3.26 | 3.23 | 3.27 | 3.19 | 3.27 |
Favorable attitude toward NMR test (%) | 75.0 | 77.8 | 77.8 | 78.0 | 77.5 |
Favorable attitude toward PRS test (%) | 78.7 | 78.5 | 75.0 | 74.4 | 71.4 |
Biosample measurements | |||||
Nicotine metabolite ratio (3-HC/cotinine) | 0.410 | 0.386 | 0.406 | 0.383 | |
Fast metabolizer (%) | 56.7 | 53.5 | 58.1 | 53.5 | |
Slow metabolizer (%) | 35.8 | 37.9 | 30.2 | 39.5 | |
Invalid result (%) | 7.5 | 8.6 | 11.6 | 7.0 | |
Respiragene™ polygenic risk score (1–10) | 5.78 | 5.57 | 5.53 | 5.67 | |
High risk (%) | 38.8 | 39.7 | 41.9 | 37.2 | |
Higher risk (%) | 31.3 | 34.5 | 34.9 | 34.9 | |
Highest risk (%) | 29.9 | 25.9 | 23.3 | 27.9 | |