The temporal association between suicide and comorbid mental disorders in people treated for substance use disorders: a National registry study

Table 2 The temporal association between suicide and comorbid mental disorders

Variable	Model 1		Model 2		Model 3
Variable	IRR (95% CI)	p	IRR (95% CI)	p	IRR (95% CI)	p
Comorbid mental disorders
No comorbidity	1 (Ref)		1 (Ref)		1 (Ref)
Psychosis/bipolar disorder (F20-F31)	0.38 (0.31–0.49)	< 0.001	0.39 (0.31–0.49)	< 0.001	0.67 (0.53–0.85)	< 0.001
Depressive/anxiety disorder (F32-F49)	0.57 (0.48–0.68)	< 0.001	0.55 (0.46–0.66)	< 0.001	0.86 (0.72–1.03)	0.106
Personality disorders (F60-F69)	0.32 (0.24–0.43)	< 0.001	0.35 (0.26–0.49)	< 0.001	0.56 (0.42–0.77)	< 0.001
Gender
Male			1 (Ref)		1 (Ref)
Female			0.89 (0.75–1.05)	0.165	0.96 (0.0.82–1.12)	0.583
Age			1.01 (1.01–1.02)	< 0.001	1.01 (1.00–1.01)	0.083
Substance use disorder
Alcohol related disorders (F10)			1 (Ref)		1 (Ref)
Opiate related disorders (F11)			0.87 (0.69–1.10)	0.237	1.00 (0.81–1.25)	0.988
Cannabis related disorders (F12)			1.02 (0.76–1.39)	0.898	1.05 (0.80–1.39)	0.745
Sedative, hypnotic, or anxiolytic related disorders (F13)			1.36 (1.03–1.82)	0.032	1.35 (1.04–1.78)	0.023
Other substance related disorders (F14-F16)			1.03 (0.75–1.44)	0.858	1.03 (0.76–1.41)	0.855
Multiple substance related disorders (F19)			1.08 (0.86–1.37)	0.491	1.11 (0.89–1.39)	0.317
Deliberate self-harm
No deliberate self-harm last year			1 (Ref)		1 (Ref)
Deliberate self-harm last year			0.78 (0.61–1.01)	0.049	0.94 (0.74–1.20)	0.593
Number of admissions
0					1 (Ref)
1					0.74 (0.61–0.91)	0.002
≥ 2					0.37 (0.37–0-56)	< 0.001
Number of outpatient contacts
0					1 (Ref)
1–10					0.64 (0.50–0.82)	< 0.001
≥ 11					0.28 (0.22–0.37)	< 0.001

Model 1 = Adjusted for seasonality. Model 2 = Model 1 adjusted for gender, age, substance use disorder and deliberate self-harm. Model 3 = Model 2 adjusted for number of in- and outpatient contacts in SUD and mental health services. Significant differences (p < 0.05) are marked with bold text
Negative binomial regression models of the association between number of weeks from the last contact and comorbid mental disorders in SUD patients who died by suicide within one year after contact with SUD or mental health services

ISSN: 1940-0640