Skip to main content

Table 5 Average number of months spent retained on buprenorphine above the retention thresholds overall and by the presence of cocaine or hazardous alcohol use at initiation restricted to 2 years after initiating buprenorphine treatment among participants with HIV and opioid use disorder in the Johns Hopkins HIV Clinical Cohort, 2013-2020

From: Measuring time in buprenorphine treatment stages among people with HIV and opioid use disorder by retention definition and its association with cocaine and hazardous alcohol use

Retention definition

Overall

Cocaine use

Hazardous alcohol use

No

Yes

Difference

No

Yes

Difference

Retention 1  ≥ 180 days of treatment without > 7-day gap

6.4 (4.1, 8.9)

4.1 (3.0, 5.2)

2.3 (1.2, 3.8)

1.8 (0.1, 3.5)

3.7 (2.7, 4.8)

2.8 (1.3, 4.5)

0.9 (–1.0, 2.8)

Retention 2  ≥ 180 days of treatment without > 30-day gap

7.5 (5.1, 10.2)

5.0 (3.8, 6.3)

2.5 (1.3, 3.9)

2.5 (0.6, 4.2)

4.5 (3.4, 5.7)

3.1 (1.6, 4.9)

1.4 (–0.6, 3.4)

Retention 3  ≥ 90 days of treatment without > 7-day gap

9.0 (6.2, 12.1)

5.7 (4.4, 7.1)

3.3 (1.8, 5.0)

2.4 (0.4, 4.4)

5.2 (4.0, 6.5)

4.0 (2.1, 6.0)

1.2 (–1.1, 3.5)

Retention 4  ≥ 90 days of treatment without > 30-day gap

10.4 (7.5, 13.7)

6.8 (5.4, 8.4)

3.6 (2.1, 5.3)

3.2(1.1, 5.3)

6.1 (4.9, 7.5)

4.4 (2.5, 6.6)

1.7 (–0.7, 4.1)

  1. The separate models for recent cocaine use and hazardous alcohol use applied multiple imputation and bootstrap estimation techniques (refer to Methods section 2.4 for more detail). The "Overall" column presents combined estimations from the models evaluating differences in cocaine use. Hence, the sum of the "No" and "Yes" columns in the cocaine use category equates to the value in the "Overall" column. Small discrepancies (1–2%) may be observed between the "Overall" column and the summed values of the "No" and "Yes" columns in the hazardous alcohol use category. These slight variations are anticipated outcomes of bootstrap estimation