From: Public sector low threshold office-based buprenorphine treatment: outcomes at year 7
Baseline or induction-related characteristic | All patients, n = 477 | Inductions, n = 302 | ||||||
---|---|---|---|---|---|---|---|---|
Hazard ratio | 95% CI | Adjusteda HR | 95% CI | Hazard ratio | 95% CI | Adjustedb HR | 95% CI | |
Age (increasing by year) | 0.99 | 0.97–1.00 | 0.98 | 0.97–1.00 | 0.99 | 0.97–1.00 | 0.99 | 0.97–1.00 |
Unemployed | 0.87 | 0.68–1.10 | – | – | 0.72 | 0.54–0.95 | 0.74 | 0.54–1.01 |
Year of First Visit (ref. 2007) | ||||||||
2008 | 0.66 | 0.45–0.96 | 0.81 | 0.54–1.20 | 1.02 | 0.63–1.66 | 1.10 | 0.62–1.96 |
2009 | 0.65 | 0.48–0.88 | 0.67 | 0.49–0.91 | 0.78 | 0.55–1.11 | 0.94 | 0.64–1.38 |
2010 | 0.75 | 0.55–1.04 | 0.75 | 0.54–1.04 | 0.72 | 0.48–1.07 | 0.88 | 0.57–1.35 |
2011 | 0.67 | 0.47–0.97 | 0.70 | 0.49–1.01 | 0.83 | 0.54–1.28 | 1.00 | 0.63–1.58 |
2012 | 0.62 | 0.36–1.06 | 0.61 | 0.35–1.05 | 0.61 | 0.31–1.22 | 0.67 | 0.33–1.36 |
2013 | 0.64 | 0.29–1.38 | 0.62 | 0.29–1.34 | 0.60 | 0.24–1.50 | 0.70 | 0.28–1.78 |
Inducted | 1.71 | 1.36–2.16 | 1.46 | 1.10–1.93 | – | – | – | – |
Prior buprenorphine | 1.29 | 0.49–0.82 | – | – | 0.79 | 0.60–1.04 | 0.79 | 0.58–1.06 |
Heroin use, active | 1.59 | 1.27–1.99 | 1.25 | 0.96–1.64 | 1.20 | 0.89–1.61 | 1.27 | 0.93–1.75 |
Cocaine use, active | 1.32 | 1.03–1.71 | 1.18 | 0.90–1.54 | 1.22 | 0.91–1.63 | 1.15 | 0.83–1.59 |
Outpatient counseling, active | 0.97 | 0.72–1.31 | – | – | 0.81 | 0.54–1.21 | – | – |
12-step attendance, active | 1.01 | 0.79–1.29 | – | – | 1.02 | 0.77–1.37 | – | – |
Any induction-related AE | – | – | – | – | 1.24 | 0.84–1.81 | – | – |
Methadone-to-buprenorphine induction | – | – | – | – | 1.02 | 0.64–1.64 | – | – |