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Table 6 Optimal and most accurate AUDIT-C thresholds

From: Validation of the AUDIT-C in adults seeking help with their drinking online

Drinking category Selected thresholds by sex, evaluations with and without optimism Sensitivity (%) (95% CI) Specificity (%) (95% CI) LR+c (95% CI) LR−d (95% CI) Sensitivity + specificity % Correctly classified (95% CI)
Above weekly limitsa Optimal Female ≥8 With optimism 69.78 (67.64, 71.85) 81.92 (75.45, 87.29) 3.86 (3.58, 4.16) 0.37 (0.27, 0.51) 151.7 70.82 (68.80, 72.78)
Optimism-adjusted 76.33 (74.34, 78.24) 72.88 (65.70, 79.28) 2.81 (2.56, 3.08) 0.32 (0.25, 0.41) 149.21 76.04 (74.13, 77.87)
Male ≥8 With optimism 82.14 (80.08, 84.08) 66.29 (58.84, 73.19) 2.44 (2.19, 2.72) 0.27 (0.21, 0.34) 148.43 80.42 (78.41, 82.31)
Optimism-adjusted 85.10 (83.16, 86.89) 57.87 (50.25, 65.21) 2.02 (1.78, 2.29) 0.26 (0.21, 0.32) 142.97 82.13 (80.18, 83.96)
Most accurate Female ≥4 With optimism 99.63 (99.23, 99.85) 16.38 (11.26, 22.68) 1.19 (0.85, 1.66) 0.02 (0.01, 0.04) 116.01 92.45 (91.22, 93.56)
Optimism-adjusted 98.61 (97.98, 99.09) 25.42 (19.19, 32.50) 1.32 (1.03, 1.70) 0.05 (0.03, 0.07) 124.03 92.30 (91.07, 93.42)
Male ≥5 With optimism 99.18 (98.56, 99.57) 25.28 (19.08, 32.33) 1.33 (1.03, 1.71) 0.03 (0.02, 0.05) 124.46 91.13 (89.64, 92.46)
Optimism-adjusted 99.18 (98.56, 99.57) 25.28 (19.08, 32.33) 1.33 (1.03, 1.71) 0.03 (0.02, 0.05) 124.46 91.13 (89.64, 92.46)
Higher risk drinkingb Optimal Female ≥8 With optimism 81.90 (79.67, 83.97) 61.90 (58.39, 65.33) 2.15 (2.02, 2.28) 0.29 (0.25, 0.34) 143.80 74.33 (72.38, 76.21)
Optimism-adjusted 81.90 (79.67, 83.97) 61.90 (58.39, 65.33) 2.15 (2.02, 2.28) 0.29 (0.25, 0.34) 143.80 74.33 (72.38, 76.21)
Male ≥9 With optimism 76.71 (73.84, 79.41) 65.03 (61.41, 68.53) 2.19 (2.05, 2.34) 0.36 (0.31, 0.42) 141.74 71.60 (69.35, 73.78)
Optimism-adjusted 76.71 (73.84, 79.41) 65.03 (61.41, 68.53) 2.19 (2.05, 2.34) 0.36 (0.31, 0.42) 141.74 71.60 (69.35, 73.78)
Most accurate Female ≥8 With optimism 81.90 (79.67, 83.97) 61.90 (58.39, 65.33) 2.15 (2.02, 2.28) 0.29 (0.25, 0.34) 143.80 74.33 (72.38, 76.21)
Optimism-adjusted 81.90 (79.67, 83.97) 61.90 (58.39, 65.33) 2.15 (2.02, 2.28) 0.29 (0.25, 0.34) 143.80 74.33 (72.38, 76.21)
Male ≥9 With optimism 76.71 (73.84, 79.41) 65.03 (61.41, 68.53) 2.19 (2.05, 2.34) 0.36 (0.31, 0.42) 141.74 71.60 (69.35, 73.78)
Optimism-adjusted 76.71 (73.84, 79.41) 65.03 (61.41, 68.53) 2.19 (2.05, 2.34) 0.36 (0.31, 0.42) 141.74 71.60 (69.35, 73.78)
  1. aAbove weekly limits >14 units of alcohol in past week (women); >21 units of alcohol in past week (men)
  2. bHigher risk drinking >35 units of alcohol in past week (women); >50 units of alcohol in past week (men)
  3. cLR+ positive likelihood ratio
  4. dLR− negative likelihood ratio